Secretion of mirna-326-3p by senescent adipose exacerbates myocardial metabolism in diabetic mice

HIGHLIGHTS

  • who: Hao Lin from the Department of Cardiology, Shanghai Ninth People`s Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China have published the article: Secretion of miRNA-326-3p by senescent adipose exacerbates myocardial metabolism in diabetic mice, in the Journal: (JOURNAL)
  • what: Through surgical as well as pharmacological means the authors show that senescent adipose tissue participates in the pathogenesis of DCM in STZ mice by exacerbates myocardial metabolism through secretion of LEVs. Using the STZ murine model, here the authors show that LEVs derived from senescent adipose are responsible for inducing diastolic . . .

     

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