HIGHLIGHTS
- who: Top from the Department of Experimental and Clinical Medicine, University of Florence, Firenze, Italy have published the paper: Selection and characterization of a human ovarian cancer cell, in the Journal: (JOURNAL)
- how: Showed that verapamil partially reverted the resistant phenotype. Resistance to auranofin in the A2780/AF-R cell line was associated with a low level of cross-resistance to three of the gold compounds tested (i.e. Aubipyc Au2Phen2 and Au(NHC)Cl) as well as to oxaliplatin Activity of thioredoxin reductase To evaluate a potential role of thioredoxin reductase (TrxR) in the . . .
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