Selection of start codon during mrna scanning in eukaryotic translation initiation

HIGHLIGHTS

  • who: Ipsita Basu from the Center forUniversity of have published the Article: Selection of start codon during mRNA scanning in eukaryotic translation initiation, in the Journal: (JOURNAL) of 15/06/2021
  • what: Model the energetics of initiator tRNA (tRNAi) binding to different near-cognate codons in the yeast 48S PIC in closed conformation was studied using atomistic molecular dynamics (MD) simulations and energy calculations in the presence or absence of eIF1 and eIF1A to understand scanning21 22 using a structure of partial yeast 48S complex in PIN state (py48S)20. The authors report that the . . .

     

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