Selective ablation of p53 in pancreatic beta cells fails to ameliorate glucose metabolism in genetic, dietary and pharmacological models of diabetes mellitus

HIGHLIGHTS

• who: ETH Library and colleagues from the (UNIVERSITY) have published the article: Selective ablation of P53 in pancreatic beta cells fails to ameliorate glucose metabolism in genetic, dietary and pharmacological models of diabetes mellitus, in the Journal: (JOURNAL) of November/25,/2022
• what: The authors aimed to challenge P53BKO mice in a model with moderate to high beta cell stress.
• how: To address this the authors analyzed the phenotype of beta cell specific P53 KO mice in several complementary models of diabetes development. The results are in line with the notion that several . . .
  

   

  

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