Selective activation of the p38 mapk pathway by synthetic monophosphoryl lipid a*

HIGHLIGHTS

  • who: Caglar Cekic from the University of Colorado Health Sciences Center)All mice were kept in a specific pathogen-free animal facility at the University of Louisville, and experiments were performed under supervision of its Institutional Animal Care and Use Committee. Synthetic versions of monophosphoryl lipid A (sMLA) and diphosphoryl lipid A (sDLA) derived from the lipid A structures of E. coli LPS were purchased from Invivogen and Peptides International, respectively. Paired batches of sMLA and sDLA were prepared simultaneously by dissolving in dimethyl sulfoxide (DMSO) with gentle vortexing until particles were no longer visible have published . . .

     

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