Selective bet bromodomain inhibition as an antifungal therapeutic strategy

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  • who: Flore Mietton from the David Dornsife College of Letters, Arts and Sciences, University of Southern California, University Park Campus, Los Angeles, California, USA have published the Article: Selective BET bromodomain inhibition as an antifungal therapeutic strategy, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 18/05/2017
  • what: The authors investigate a chromatin-interacting module the bromodomain (BD) from the BET family of proteins as a potential antifungal target in Candida albicans a major human fungal pathogen. The authors show that the BET protein Bdf1 is essential in C. albicans and that mutations inactivating . . .

     

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