Selective clonal persistence of human retroviruses in vivo: radial chromatin organization, integration site, and host transcription

HIGHLIGHTS

• who: VIROLOGY and collaborators from the DepartmentLondon, UKMellon University have published the Article: Selective clonal persistence of human retroviruses in vivo: Radial chromatin organization, integration site, and host transcription, in the Journal: (JOURNAL) of 29/04/2022
• what: The aim of this study was to test two hypotheses that arise from these observations: first that specific genomic attributes of the proviral integration site in an HTLV-1-infected clone determine its survival in the host during chronic infection and second that the intranuclear position of the provirus determines clonal survival in vivo. The authors compare . . .
  

   

  

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