Selective exosome exclusion of mir-375 by glioma cells promotes glioma progression by activating the ctgf-egfr pathway

HIGHLIGHTS

  • who: Xiangdong Xu from the Zhujiang Hospital, Southern Medical University, Guangzhou, China have published the research: Selective exosome exclusion of miR-375 by glioma cells promotes glioma progression by activating the CTGF-EGFR pathway, in the Journal: (JOURNAL)
  • what: Prior to the present study, no evidence for the occurrence of this phenomenon in glioma had been presented.
  • how: These results indicated that exosome-mediated miR-375 release impacts the activation status of the CTGF-EGFR pathway. The results showed that miR-375 overexpression inhibited glioma growth migration and invasion demonstrating that miR-375 . . .

     

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