Selective histone deacetylase 6 inhibitors restore cone photoreceptor vision or outer segment morphology in zebrafish and mouse models of retinal blindness

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  • who: Breandán N. Kennedy from the UCD Conway Institute, University College Dublin, Dublin, Ireland, UCD School of Biomolecular and Biomedical Science, Department of Biotechnology, Chemistry and Pharmacy, Department of Excellence, University of Siena, Siena, Italy have published the paper: Selective Histone Deacetylase 6 Inhibitors Restore Cone Photoreceptor Vision or Outer Segment Morphology in Zebrafish and Mouse Models of Retinal Blindness, in the Journal: (JOURNAL)
  • what: The aim of this study was to identify HDAC6 inhibitors that elicits robust neuroprotection in genetic model(s) of retinal blindness and to understand the molecular mechanism through which . . .

     

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