Selective one-pot multicomponent synthesis of n-substituted 2,3,5-functionalized 3-cyanopyrroles via the reaction between -hydroxyketones, oxoacetonitriles, and primary amines

HIGHLIGHTS

• who: Mengxin Xia et al. from the School of Chemical and Biomedical Engineering, Nanyang Technological University, Nanyang Drive have published the paper: Selective One-Pot Multicomponent Synthesis of N-Substituted 2,3,5-Functionalized 3-Cyanopyrroles via the Reaction between -Hydroxyketones, Oxoacetonitriles, and Primary Amines, in the Journal: Molecules 2022, 27, x FOR PEER REVIEW of /2022/
• what: The structures of the 3-cyanopyrroles were confirmed by single-crystal X-ray diffraction and NMR; this work provides a general and practical entry to pyrrole scaffolds suitably decorated for the synthesis of various bioactive pyrroles in . . .
  

   

  

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