Selective overexpression of cytoglobin in stellate cells attenuates thioacetamide-induced liver fibrosis in mice

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• who: Nguyen Thanh Hai from the Cygb-, mCherry BAC transgenic mice were generated by pronuclear injection of C BL/ JJcl embryos (Clea Japan Inc [, ]Kanagawa, Japan). Transgenic founders of the BAC transgenic construct were assessed by Southern blotting of XbaI-digested tail DNA probed by the [ P]-labelled mCherry gene fragment. Nine of , progenies (14%) contained the transgene, as detected by Southern blotting of tail DNA. Several transgenic founder mice were bred with mice of the same strain. Only mice with , copies of the Cygb-transgene were used for this study. No obvious gross phenotypic differences were . . .
  

   

  

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