HIGHLIGHTS
- who: Sean Brennan and Richard D. Rainbow from the Fourth Military Medical University, China have published the Article: Selective protein kinase C inhibition switches time-dependent glucose cardiotoxicity to cardioprotection, in the Journal: (JOURNAL)
- what: In this manuscript the authors investigate the time-dependence of the damaging effect of enhanced glycolytic metabolism and whether inhibition of protein kinase C (PKC) u03b1 and u03b2 isoforms can reduce the onset of these damaging effects. The authors show that exposure to elevated glucose for >7.5 min decreased contractile recovery following a period of metabolic inhibition, suggesting that . . .
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