Selective regulation of tuft cell-like small cell lung cancer by novel transcriptional co-activators c11orf53 and colca2

HIGHLIGHTS

  • who: Chen Zhou from the (UNIVERSITY) have published the paper: Selective regulation of tuft cell-like small cell lung cancer by novel transcriptional co-activators C11orf53 and COLCA2, in the Journal: (JOURNAL)
  • what: Based on the findings discussed above, the authors propose that POU2AF1/C11orf53/COLCA2 are a family of co-activators for POU2F1/2/3 to regulate SCLC and possibly additional cancers such as multiple myeloma (Fig 1n).
  • how: Based on the analysis the authors hypothesized that C11orf53/COLCA2 and POU2F3 may work in the same pathway to regulate the growth of . . .

     

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