Selective targeting of md2 attenuates intestinal inflammation and prevents neonatal necrotizing enterocolitis by suppressing tlr4 signaling

HIGHLIGHTS

• who: Dabin Huang et al. from the Upstate Medical University, United States have published the research: Selective targeting of MD2 attenuates intestinal inflammation and prevents neonatal necrotizing enterocolitis by suppressing TLR4 signaling, in the Journal: (JOURNAL)
• what: This model has been proven to be an ideal NEC modeling method that reproduces the typical pathophysiological changes in NEC by combining a variety of pathogenic factors. This study showed that targeting MD2 to block the activation of TLR4 reduces excessive inflammatory storms, intestinal barrier function injury and intestinal cell apoptosis in NEC patients.
• how: These . . .
  

   

  

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