Selective yolk deposition and mannose phosphorylation of lysosomal glycosidases in zebrafish*

HIGHLIGHTS

• who: Xiang Fan from the Xiang Fan, Maximilian Klein, Heather RFlanagan-Steet, and Richard Steet, From the Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia , The regulation and function of lysosomal hydrolases during yolk consumption and embryogenesis in zebrafish are poorly understood. In an effort to better define the lysosomal biochemistry of this organism, we analyzed the developmental expression, biochemical properties, and function of several glycosidases in zebrafish eggs, embryos, and adult tissues. Our results demonstrated that the specific activity of most enzymes increases during embryogenesis, likely reflecting a greater need for turnover within the embryo . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.