HIGHLIGHTS
- who: Kenneth C. McCullough and collaborators from the Institute of Virology and Immunology, Mittelhaeusern, Switzerland have published the article: Self-Amplifying Replicon RNA Vaccine Delivery to Dendritic Cells by Synthetic Nanoparticles, in the Journal: Vaccines 2014, 2, 735-754 of 29/08/2014
- what: The present review presents how such advances are being applied to the delivery of a new form of RNA vaccine replicons (RepRNA) carrying inserted foreign genes of interest encoding vaccine antigens. The aims focus on nanoparticle structures enhancing DC interaction, the consideration of cellular endocytic pathways for determining the outcome of . . .
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