Self-assembled dna nanostructure containing oncogenic mirna-mediated cell proliferation by downregulation of foxo1 expression

HIGHLIGHTS

• who: Avishek Kar from the (UNIVERSITY) have published the research work: Self-assembled DNA nanostructure containing oncogenic miRNA-mediated cell proliferation by downregulation of FOXO1 expression, in the Journal: (JOURNAL)
• what: In this study self-assembled branched DNA (bDNA) nanostructures containing oncogenic miRNAs were designed and transfected to the MCF7 cell line to decipher the FOXO1 expression. bDNA containing oncogenic miRNAs 27a 96 and 182 synergistically downregulate the expression of FOXO1 in MCF7 cells. Keeping this as background, this study shows the role of exogenous oncomiRs on the expression of FOXO1 in breast cancer cell . . .
  

   

  

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