Self-sustained regulation or self-perpetuating dysregulation: ros-dependent hif-yap-notch signaling as a double-edged sword on stem cell physiology and tumorigenesis

HIGHLIGHTS

• who: ROS and colleagues from the Institute of Physics, Academia Sinica, Taipei, Taiwan University of Southern California have published the paper: Self-Sustained Regulation or Self-Perpetuating Dysregulation: ROS-dependent HIF-YAP-Notch Signaling as a Double-Edged Sword on Stem Cell Physiology and Tumorigenesis, in the Journal: (JOURNAL)
• what: In the module boxes, the authors discuss how molecular oxygen O2 regulates HIF stability (Module Box I), how ROS regulate HIF stability (Module Box II), and the X-ROS signaling (Module Box III). The authors focus on the coupling of NOX with cell mechanics and . . .
  

   

  

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