Semi-synthesis of n-aryl amide analogs of piperine from piper nigrum and evaluation of their antitrypanosomal, antimalarial, and anti-sars-cov-2 main protease activities

HIGHLIGHTS

• who: Rattanaporn Wansri et al. from the Department of Pharmacognosy and Botany, Faculty of, Natural Products and Nanoparticles Research Unit (NP2), Chulalongkorn University, Bangkok, Thailand have published the Article: Semi-Synthesis of N-Aryl Amide Analogs of Piperine from Piper nigrum and Evaluation of Their Antitrypanosomal, Antimalarial, and Anti-SARS-CoV-2 Main Protease Activities, in the Journal: (JOURNAL)
• what: The authors report for the first time, the chemical and biological aspects of the methoxy-substituted phenyl piperamides 4 and 5.
• how: The results indicated that compounds 4 and 5 which contained 24 . . .
  

   

  

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