Semi-synthetic dihydrotestosterone derivatives modulate inherent multidrug resistance and sensitize colon cancer cells to chemotherapy

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  • who: Ferenc Istvu00e1n Nagy et al. from the Department of Biochemistry and Molecular Biology, Doctoral School of Biology, University of, Heidelberg, Germany have published the article: Semi-Synthetic Dihydrotestosterone Derivatives Modulate Inherent Multidrug Resistance and Sensitize Colon Cancer Cells to Chemotherapy, in the Journal: Pharmaceutics 2023, 15, x FOR PEER REVIEW of /2023/
  • what: The aim of this present work was to examine the sensitizing potential of semi-synthetic androstane derivatives on inherently multidrug-resistant Colo 320 colon adenocarcinoma cells. The authors examined the capability of acetylated and deacetylated androstano-arylpyrimidines to inhibit the efflux . . .

     

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