HIGHLIGHTS
SUMMARY
Parkinson`s disease (PD) is an age-related neurodegenerative pathology, characterized by nigrostriatal dopaminergic degeneration. With regard to individuals affected by PD, Castiglia et_al, analysed HR in patients during ON phase. Buckley et_al showed higher JR values in subjects with PD when compared to healthy controls, demonstrating the importance of upper body variables during gait, in conjunction to the spatiotemporal gait parameters. In the previous study the authors showed how the TDI could distinguish the PD individuals before and after a sub-clinical dose of L-DOPA intake, with the PD patients in OFF . . .
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