Sensitization of resistant cells with a bet bromodomain inhibitor in a cell culture model of deep intrinsic resistance in breast cancer

HIGHLIGHTS

  • who: Balraj Singh and collaborators from the Department of Breast Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA have published the research: Sensitization of Resistant Cells with a BET Bromodomain Inhibitor in a Cell Culture Model of Deep Intrinsic Resistance in Breast Cancer, in the Journal: Cancers 2023, 2036 of /2023/
  • what: To provide a proof of concept for the usefulness of the cell culture model for evaluating cancer therapies, in this study the authors evaluated a well-known BET bromodomain 3 of 14 inhibitor, JQ1, which has been shown . . .

     

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