Separase control and cohesin cleavage in oocytes: should i stay or should i go?

HIGHLIGHTS

• who: Katja Wassmann from the (UNIVERSITY) have published the research: Separase Control and Cohesin Cleavage in Oocytes: Should I Stay or Should I Go?, in the Journal: Cells 2022, 3399 of /2022/
• what: In this model, it was proposed that the APC/C would have a higher affinity towards phosphorylated -thus free- securin, thereby ensuring degradation of free securin before separase-bound securin .
• future: Whether Pin1 has a physiological role in the transition from meiosis I to meiosis II and/or at exit from meiosis II is another open issue that needs to . . .
  

   

  

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