Septin6 and septin7 gtp binding proteins regulate ap- 3- and escrt-dependent multivesicular body biogenesis

HIGHLIGHTS

• who: Sofia Traikov et al. from the Biotechnological Center, Technische Universität Dresden, Dresden, Germany, School of Life and Health Sciences, Aston University, Birmingham, United Kingdom have published the research work: Septin6 and Septin7 GTP Binding Proteins Regulate AP- 3- and ESCRT-Dependent Multivesicular Body Biogenesis, in the Journal: PLOS ONE | www.plosone.org
• what: The authors show that SEPT6 and SEPT7 complexes bound to F-actin regulate protein sorting during multivesicular body (MVB) biogenesis. SEPT6 and SEPT7 bound to F-actin regulate the motility of AP-3-positive endosomes and AP-3 dynamics SEPT6 . . .
  

   

  

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