HIGHLIGHTS
- who: Chun Gong from the Stem Cell Institute University of Cambridge, Puddicombe Way, Cambridge , AW, UK have published the article: Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis, in the Journal: (JOURNAL)
- what: The authors show that loss-of-function DDX3X mutations are also enriched MYC-translocated diffuse large B cell lymphoma and reveal functional cooperation between mutant DDX3X and DDX3X promotes the translation of mRNA encoding components of the core translational machinery thereby driving global protein synthesis. The authors investigate the role of DDX3X mutations in BL and . . .
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