Serotype conversion gene rfbt is directly regulated by histone-like nucleoid structuring protein (h-ns) in v. cholerae o1

HIGHLIGHTS

• who: ufeffYuufeff ufeffHanufeff from the AandF, China have published the research: Serotype conversion gene ufeffrfbTufeff is directly regulated by histone-like nucleoid structuring protein (H-NS) in ufeffV. choleraeufeff O1, in the Journal: (JOURNAL)
• what: The authors show that H-NS negatively regulates the transcription of the serotype-switching gene rfbT by directly binding to its promoter region, whereas fis does not affect its expression.
• how: Together these results showed that H-NS negatively regulates rfbT expression. To further clarify the real H-NS binding_site in the rfbT promoter and dissect the binding . . .
  

   

  

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