HIGHLIGHTS
- who: L S Ang from the InstitutUniversity of Alberta, Edmonton, Alberta, Canada have published the paper: Serpina3n attenuates granzyme B-mediated decorin cleavage and rupture in a murine model of aortic aneurysm, in the Journal: (JOURNAL)
- what: Based on the previous results showing an extracellular role for GZMB in aneurysm pathology the purpose of this study was to determine whether SA3N could attenuate AAA in mice. The authors have previously shown that GZMB degrades decorin in_vitro6 and here the authors demonstrate that preincubation with SA3N is capable of preventing cleavage by GZMB . The authors propose . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.