Serum α-kl, a potential early marker of diabetes complications in youth with t1d, is regulated by mirna

HIGHLIGHTS

  • who: Zhenwei Gong from the State University of New Jersey, United States have published the paper: Serum u03b1-KL, a potential early marker of diabetes complications in youth with T1D, is regulated by miRNA, in the Journal: (JOURNAL)
  • what: The authors show that miR-192 is an upstream regulator of KL, and induces markers of oxidative stress, inflammation, and senescence in_vitro. The study shows that KL is negatively correlated significantly with HbA1c, and this is consistent with a previous study from Poland in a pediatric population. The authors show that overexpression of miR-192 inhibits . . .

     

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