Sestrin2 signaling pathway regulates podocyte biology and protects against diabetic nephropathy

HIGHLIGHTS

  • who: Sestrin and colleagues from the School of Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran have published the Article: Sestrin2 Signaling Pathway Regulates Podocyte Biology and Protects against Diabetic Nephropathy, in the Journal: Journal of Diabetes Research of 10/02/2023
  • what: Sestrin2 can modulate several molecular signaling pathways involved in the pathogenesis of diabetic nephropathy.

SUMMARY

    The most important histological alterations in diabetic nephropathy are mesangial cell dysfunction and podocyte loss. Any attempt to improve diabetic nephropathy must be able to prevent these changes, as previous studies mainly . . .

     

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