Setting the stage for insulin granule dysfunction during type-1-diabetes: is er stress the culprit?

HIGHLIGHTS

• who: Aishwarya A. Makam and collaborators from the Indian Institute of Science (IISc), Bengaluru, India Unit of Metabolic Physiology, University of Gothenburg, , Gothenburg, Sweden have published the article: Setting the Stage for Insulin Granule Dysfunction during Type-1-Diabetes: Is ER Stress the Culprit?, in the Journal: Biomedicines 2022, x of /2022/
• what: In this review the authors focus on the cellular elements such as ER (endoplasmic reticulum) stress and its consequences for T1D pathogenesis. The authors explore the possible associations between ER stress leading to defects in insulin secretion and ultimately u03b2-cell destruction . . .
  

   

  

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