HIGHLIGHTS
SUMMARY
Coronavirus disease 2019 (COVID-19) is a potentially life-threatening respiratory disorder caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Of note, several other immune cell subsets, including T_cell and dendritic cell subsets, also expressed specific CCR genes (Fig 1d, Additional file 1: Figs S2-S3). Chromatin interaction profiles from primary immune cells (measured by promoter-capture Hi-C ) revealed extensive monocyte/macrophage-specific chromatin interactions between the three ACRs, as exemplified by CCR1 promoter interaction profiles in monocyte-derived macrophages and T_cells (Fig 1e, Additional file 1: Fig S4a . . .
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