Severe fever with thrombocytopenia syndrome virus replicates in brain tissues and damages neurons in newborn mice

HIGHLIGHTS

• who: Rui Chen from the C BL/, pregnant mice were purchased from the experimental Animal Center of China Three Gorges UniversityPregnant mice were raised under suitable conditions to normal delivery. One-day-old newborn mice were divided into , groups (n=, to, ). The newborn mice were injected intraperitoneally with the same amount of SFTSV (, × ­ TCID50) and six mock-infected mice were used as controls. At each time point of , h, h, h, h, h, days, days, and , days after infection, the mice were sacrificed, their skulls were opened, and brain tissues were taken out and frozen at, ℃. The . . .
  

   

  

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