Sex disparities in mgmt promoter methylation and survival in glioblastoma: further evidence from clinical cohorts

HIGHLIGHTS

  • who: Anja Smits and collaborators from the DepartmentGothenburg University have published the Article: Sex Disparities in MGMT Promoter Methylation and Survival in Glioblastoma: Further Evidence from Clinical Cohorts, in the Journal: (JOURNAL) of 28/01/2021
  • what: Taken together, the authors provide further evidence for sex-bound disparities in the epigenetic regulation of IDHwt GBM, exemplified by the MGMT status of the tumor, which could contribute to a survival advantage for female patients.

SUMMARY

    Recent studies suggest an overrepresentation of MGMT promoter methylated tumors in females with IDHwt glioblastoma (GBM) compared . . .

     

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