HIGHLIGHTS
- who: Gang Zhai from the (UNIVERSITY) have published the article: Sex-specific differences in zebrafish brains, in the Journal: (JOURNAL)
- what: This study provides comprehensive information to further understand zebrafish brain sex differentiation and its associated challenges. Interestingly, the study showed that in the steroid hormone synthesizing gene cytochrome P450, family 17, subfamily A1 (cyp17a1) knockout zebrafish, the dio2 expression in the brain was downregulated threefold in both RNA sequencing and qPCR, while a rescue experiment with androgens upregulated dio2 levels by twofold compared to the nonrescued fish . In this study, the sex was determined . . .
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