Sexual dimorphism of early transcriptional reprogramming in degenerating peripheral nerves

HIGHLIGHTS

  • who: Andrei V. Chernov from the Indiana University, United States have published the paper: Sexual dimorphism of early transcriptional reprogramming in degenerating peripheral nerves, in the Journal: (JOURNAL)
  • what: This study of degenerating (distal) identified new sexually dimorphic protein-coding and non-coding (nc)RNAs and respective signaling pathways specific to peripheral nerve remodeling.

SUMMARY

    Machinery required to support their robust phenotypic changes induced by injury, including de-differentiation, accompanied by myelin protein gene silencing and glial fibrillary acidic protein (GFAP) activation, followed by neuregulin-epidermal growth factor receptor (EGFR, also . . .

     

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