Sgrp78 enhances selective autophagy of monomeric tlr4 to regulate myeloid cell death

HIGHLIGHTS

• who: Zhenghao Wu from the Animals C BL/, mice (HFK Bioscience, Beijing, China), C BL/, background , knockout (KO) mice (kindly donated by Professor Timothy RBilliar, University of Pittsburgh, Pittsburgh, PA, USA), and , KO mice (The Jackson Laboratory, Bar Harbor, ME, USA) were bred in a specific pathogenfree facility, and female mice were utilized at, weeks of age. have published the research: sGRP78 enhances selective autophagy of monomeric TLR4 to regulate myeloid cell death, in the Journal: (JOURNAL) of 17/02/2022
• what: The work demonstrated that sGRP78 suppresses TLR4dependent inflammatory responses through multiple mechanisms (Fig . . .
  

   

  

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