‘shared-hook’ and ‘changed-hook’ binding activities of herpesviral core nuclear egress complexes identified by random mutagenesis

HIGHLIGHTS

• who: Josephine Lu00f6sing and collaborators from the Institute for Clinical and Molecular Virology, Friedrich-Alexander-Universitu00e4t Erlangen-Nu00fcrnberg (FAU), Erlangen, Germany have published the paper: u2018Shared-Hooku2019 and u2018Changed-Hooku2019 Binding Activities of Herpesviral Core Nuclear Egress Complexes Identified by Random Mutagenesis, in the Journal: Cells 2022, x of /2022/
• what: This approach of random 10 of 29 10 of 28 screening . With this study, the authors aimed to identify a common structural panherpesviral NEC scaffold that enables hook-into-groove interactions between NEC proteins derived from members of different viral subfamilies.
• how . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.