HIGHLIGHTS
- who: Kyoji Ohyama from the Institute of Genetics China University of Dundee, United Kingdom have published the paper: SHH and Notch regulate SOX9C progenitors to govern arcuate POMC neurogenesis, in the Journal: (JOURNAL)
- what: By perturbing SHH and Notch signalling in an ex vivo assay, the authors demonstrate that both pathways are required for the maintenance of SOX9+ cycling VZ progenitors upstream of POMC neuronal differentiation. The TFs studied in this work have a multitude of distinct cellular roles in multiple tissues, and each has also been linked to the regulation of EMT. Although this . . .
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