Shp-2-induced m2 polarization of tumor associated macrophages via il-4 regulate colorectal cancer progression

HIGHLIGHTS

• who: Zhihan Li and colleagues from the Mahidol University, Thailand have published the article: SHP-2-induced M2 polarization of tumor associated macrophages via IL-4 regulate colorectal cancer progression, in the Journal: (JOURNAL)
• what: Pharmacological inhibition the phosphatase activity of SHP-2 could serve as potential therapeutic targets of CRC.
• how: The wound healing assay results showed that after 24 and 48 hours the scratch width of CRC cells co-cultured with IL-4treated macrophages was apparently smaller than that in control group indicating that the migration rate of tumor cells to . . .
  

   

  

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