Shp2 inhibition enhances yes-associated protein-mediated liver regeneration in murine partial hepatectomy models

HIGHLIGHTS

• who: Ryan D. Watkins and colleagues from the DepartmentMedical University Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA have published the article: SHP2 inhibition enhances Yes-associated protein-mediated liver regeneration in murine partial hepatectomy models, in the Journal: (JOURNAL)
• how: The authors examined the effects of YAP activation with a selective SHP1/SHP2 inhibitor NSC-87877 on liver regeneration in murine partial hepatectomy models.
• future: The specific mechanisms contributing to the enhanced regeneration the authors observed will need to be evaluated in future studies however these preclinical data indicate that activating YAP through . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.