Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket

HIGHLIGHTS

  • who: Edward N. Schmidt from the Human samples All experiments involving human blood samples and placental sample collection were approved by the human research ethics board (HREB) biomedical panel at the University of Alberta have published the article: Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket, in the Journal: (JOURNAL) of 26/08/2022
  • how: For Siglec-4 the authors considered that serum has ligands that GM2 suggest that the binding of a Siglec and a ganglioside in solution is not representative of the same interaction in a bilayer . . .

     

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