HIGHLIGHTS
- who: Bashar M. Thejer and collaborators from the School of Dentistry and Medical Sciences, Charles Sturt University, Wagga Wagga, NSW, Australia have published the research: Sigma-2 Receptor Ligand Binding Modulates Association between TSPO and TMEM97, in the Journal: (JOURNAL)
- what: The authors investigate the contributions of and to S2R activity in MCF7 breast adenocarcinoma and MIA PaCa-2 (MP) pancreatic carcinoma cells. The authors show that both TSPO and TMEM97 proximal and functional interactions between TMEM97 and TSPO, as well as with the are required for SW120 binding. Given these premises, the authors reason . . .
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