Signaling pathways in rheumatoid arthritis: implications for targeted therapy

HIGHLIGHTS

  • who: Qian Ding from the Approved in China have published the research: Signaling pathways in rheumatoid arthritis: implications for targeted therapy, in the Journal: (JOURNAL) of 15/09/2022
  • what: This study provided evidence that GATA4 has a previously unknown function as a modulator of RA angiogenesis, and data validate GATA4 as the therapeutic target in RA mice.
  • how: These results indicated that JAK2 took part in the pathogenesis of RA and inhibition of JAK2 could treat RA by inhibiting the generation of cytokines and the T and B-lymphocytes activation. The results . . .

     

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