Signaling underlying kappa opioid receptor-mediated behaviors in rodents

HIGHLIGHTS

• who: Lee-Yuan Liu-Chen from the Indian Institute of Technology (BHU), University of Udine, Italy have published the Article: Signaling underlying kappa opioid receptor-mediated behaviors in rodents, in the Journal: (JOURNAL)
• what: U50,488H-promoted KOR phosphorylation at S356 and T357 occurred to much lower extents than at T363 and S369 and phosphorylation of T363 and S369 occurred before that of S356 and T357, thus the authors focused on T363 and S369 phosphorylation.

SUMMARY

Biased agonism or functional selectivity is a popular concept in GPCR signaling (Whalen et_al, 2011 . . .

 



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