Silencing of circ_002136 sensitizes gastric cancer to paclitaxel by targeting the mir 5p/ hmga1 axis

HIGHLIGHTS

  • who: HMGA and colleagues from the (UNIVERSITY) have published the research: Silencing of circ_002136 sensitizes gastric cancer to paclitaxel by targeting the miR 5p/ HMGA1 axis, in the Journal: (JOURNAL)
  • what: The aim of this study was to clarify the molecular mechanisms of circ_002136 in Taxresistant GC.
  • how: The obtained data showed that circ_002136 was significantly upregulated in GC tissues compared to paired non-tumor tissues . The results indicated that knockdown of circ_002136 apparently enhanced the level of miR-16-5p in SGC7901/Tax and BGC823/Tax cells . The obtained experimental data indicated . . .

     

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