HIGHLIGHTS
- who: Jae Hyun Cho from the (UNIVERSITY) have published the research: Silencing of hypothalamic FGF11 prevents diet-induced obesity, in the Journal: (JOURNAL)
- what: The authors report the central role of FGF11 in the regulation of metabolism. The authors report that hypothalamic FGF11 knockdown improved metabolic features under high-fat conditions. The study showed that FGF11 knockdown in the hypothalamus improves glucose and insulin intolerance. The authors first demonstrated that hypothalamic Fgf11 gene_expression was significantly increased by 16-week-HFD, but not by fasting.
- future: Although further study will be needed to understand . . .
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