Silvi, an open-source pipeline for t-cell epitope selection

HIGHLIGHTS

  • who: Joana Pissarra et al. from the , University of (I-MUSE), France, CBGP have published the research work: SILVI, an open-source pipeline for T-cell epitope selection, in the Journal: PLOS ONE of 20/09/2021
  • what: Considering all this, the authors propose that a robust epitope selection process should start with binding affinity prediction analysis by at least two different algorithms, of a strong antigen pool (highly abundant, conserved, exposed and accessible proteins, expressed in the appropriate timing during infection). By comparing core predictions, the authors compare predictors and consider all potential cores . . .

     

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