Silvi, an open-source pipeline for t-cell epitope selection

HIGHLIGHTS

  • who: Joana Pissarra et al. from the , University of (I-MUSE), France, CBGP have published the Article: SILVI, an open-source pipeline for T-cell epitope selection, in the Journal: PLOS ONE of 20/09/2021
  • what: Considering all this, the authors propose that a robust epitope selection process should start with binding affinity prediction analysis by at least two different algorithms, of a strong antigen pool (highly abundant, conserved, exposed and accessible proteins, expressed in the appropriate timing during infection). By comparing core predictions, the authors compare predictors and consider all potential cores within . . .

     

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