Simple pcr assays improve the sensitivity of hiv-1 subtype b drug resistance testing and allow linking of resistance mutations

HIGHLIGHTS

  • who: Resistance Mutations et al. from the Division Stanford University have published the research: Simple PCR Assays Improve the Sensitivity of HIV-1 Subtype B Drug Resistance Testing and Allow Linking of Resistance Mutations, in the Journal: (JOURNAL)
  • what: The authors focused on developing and validating nine assays for key drug resistance mutations in subtype B HIV-1 clinical specimens as a basis for later expansion to other virus mutations and subtypes. The authors demonstrate that these assays are able to detect low-frequency drug resistance and permit easy identification of linked mutations, thus, providing . . .

     

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