Simple synthesis of multi-halogenated alkenes from 2-bromo-2-chloro-1,1,1-trifluoroethane (halothane)

HIGHLIGHTS

• who: Yukiko Karuo et al. from the Faculty of Pharmaceutical Sciences, Setsunan University, Nagaotoge-cho, Hirakata, Osaka, Japan have published the article: Simple synthesis of multi-halogenated alkenes from 2-bromo-2-chloro-1,1,1-trifluoroethane (halothane), in the Journal: (JOURNAL)
• what: The authors propose the reaction mechanism shown in Scheme 2 .

SUMMARY

The halothane structure contains two highly halogenated carbon centers, which enable halothane to participate in various reactions such as homolysis of carbon-halogen bonds and deprotonation. Multi-fluorinated compounds such as HCFC-133a (CF3CH2Cl) and HFC-134a . . .

 



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